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RS 504393
CAS No. 300816-15-3
RS 504393( —— )
Catalog No. M20120 CAS No. 300816-15-3
RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and > 100 μM for human recombinant CCR2 and CCR1).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 88 | In Stock |
|
| 10MG | 151 | In Stock |
|
| 25MG | 332 | In Stock |
|
| 50MG | 498 | In Stock |
|
| 100MG | 718 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRS 504393
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NoteResearch use only, not for human use.
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Brief DescriptionRS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and > 100 μM for human recombinant CCR2 and CCR1).
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DescriptionRS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and > 100 μM for human recombinant CCR2 and CCR1).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAutophagy
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TargetCCR
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RecptorCCR2
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Research Area——
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Indication——
Chemical Information
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CAS Number300816-15-3
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Formula Weight417.51
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Molecular FormulaC25H27N3O3
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mg/mL (23.95 mM); Water: Insoluble
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SMILESCc1oc(nc1CCN1CCC2(CC1)OC(=O)Nc1ccc(C)cc21)-c1ccccc1
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Chemical Name6-Methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-31-benzoxazine-44'-piperidin]-2(1H)-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Mirzadegan T et al. Identification of the binding site for a novel class of CCR2b chemokine receptor antagonists: binding to a common chemokine receptor motif within the helical bundle. J Biol Chem. 2000 Aug 18;275(33):25562-71.
molnova catalog
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RS 504393
RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and > 100 μM for human recombinant CCR2 and CCR1).
